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目的研究高血压、高血脂、高血糖在脑卒中后血管性痴呆(vascular dementia,VD)发生和发展过程中的作用和意义。方法本研究纳入220例脑卒中患者,均经头颅CT、MRI确诊,应用简易智力状态检查量表(MMSE)进行评分,并结合明确的脑卒中病史确诊VD,观察VD发生率,并对VD组与非VD组患者高血压、高血脂、高血糖发生率进行统计学分析。结果共发生VD46例,发生率20.9%,VD组高血压、高血脂、高血糖的发生率分别为65.2%、43.5%、26.1%,非VD组患者的发生率分别为64.4%、46.0%、20.7%,2组高血压、高血脂、高血糖的发生率比较,差异无统计学意义(P>0.05)。结论高血压、高血脂、高血糖可能并非是VD的危险因素。
Objective To investigate the role and significance of hypertension, hyperlipidemia and hyperglycemia in the pathogenesis and development of vascular dementia (VD) after stroke. Methods In this study, 220 stroke patients were included in the study. All patients were diagnosed by CT and MRI, and MMSE was used to assess the incidence of VD. The incidence of VD was observed and the VD group And non-VD group of patients with hypertension, hyperlipidemia, the incidence of hyperglycemia for statistical analysis. Results A total of 46 cases had VD, with a incidence rate of 20.9%. The incidences of hypertension, hyperlipidemia and hyperglycemia in VD group were 65.2%, 43.5% and 26.1% respectively. The incidences of non-VD group were 64.4% and 46.0% 20.7%. There was no significant difference in the incidence of hypertension, hyperlipidemia and hyperglycemia between the two groups (P> 0.05). Conclusion Hypertension, hyperlipidemia and hyperglycemia may not be risk factors for VD.