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目的:测量结肠癌病人化疗前后能量代谢和人体成分,以评估其化疗前后的营养状况。方法:选择结肠癌病人51例,采用自身对照研究方法,于化疗前2 d和化疗后第2天,采用床旁代谢仪测量静息能量代谢(REE),并采用人体成分分析仪对病人进行人体成分分析。结果:所有结肠癌病人化疗后第2天的REE与化疗前2 d比较均显著降低,且差异有显著性统计学意义(P<0.05)。化疗后体脂百分数增加,瘦体质量百分数降低,身体水分百分数增加。体脂百分数、瘦体质量百分数与身体水分百分数均值差异均有统计学意义(P<0.05)。结论:结肠癌病人化疗后静息能量消耗与化疗前比呈下降趋势,体脂百分数增加,瘦体质量百分数降低,身体水分百分数增加。
Objective: To measure the energy metabolism and human body composition of patients with colon cancer before and after chemotherapy to assess their nutritional status before and after chemotherapy. Methods: Fifty-one patients with colon cancer were selected and their self-control study method was used. Resting energy metabolism (REE) was measured by bedside metabolometer at 2 days before chemotherapy and 2 days after chemotherapy. The patient’s body composition analyzer Body composition analysis. Results: The REE on the 2nd day after chemotherapy in all colon cancer patients was significantly lower than that on the 2nd day before chemotherapy, and the difference was statistically significant (P <0.05). After chemotherapy, the percentage of body fat increases, the percentage of lean body mass decreases, and the body moisture percentage increases. Body fat percentage, lean body mass percentage and body water percentage mean difference were statistically significant (P <0.05). Conclusion: The resting energy consumption of patients with colon cancer after chemotherapy is lower than that before chemotherapy, the percentage of body fat increases, the percentage of lean body mass decreases, and the body water percentage increases.