论文部分内容阅读
慢性氟中毒,因饮水含氟量过高引起,在矿化组织内沉积氟磷灰石和氟化钙,累及骨组织,形成氟斑牙。检查中度地方性慢性氟中毒少年(15岁)13例,收集混合唾液,用分光光度测定法检查唾液内3种谷氨酸盐代谢酶含量。对照组是无氟中毒的健康少年20例。 检查结果表明慢性氟中毒少年,唾液的谷氨酸盐代谢酶含量降低(P<0.01),导致谷氨酸盐生成减少。①天门冬氨酸转氨酶含量为3.72±0.54μmol/min/L(对照组5.34±0.54),表明由天门冬氨酸盐和2-氧络戊二酸盐生成谷氨酸盐减少。②谷氨酸脱氢酶含量为4.30±0.70μmol/min/L(对照组7.86±1.61),表明2-
Chronic fluorosis, due to excessive fluoride content in drinking water, deposited in the mineralized tissue fluoride apatite and calcium fluoride, involving bone tissue, the formation of dental fluorosis. Check moderate endemic chronic fluorosis juvenile (15 years) 13 cases, collected mixed saliva, saliva by spectrophotometry three kinds of glutamate metabolism enzyme content. Control group was 20 cases of healthy children without fluoride poisoning. Examination results showed that juveniles with chronic fluorosis had a decreased level of glutamate-metabolizing enzyme in saliva (P <0.01), leading to a decrease in glutamate production. ① Aspartate aminotransferase level was 3.72 ± 0.54μmol / min / L (control group, 5.34 ± 0.54), indicating that aspartate and 2-oxo glutarate produce reduced glutamate. ② glutamate dehydrogenase content of 4.30 ± 0.70μmol / min / L (control group 7.86 ± 1.61), indicating that 2-