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目的对多发伤患者血清肌酸激酶动态变化进行临床分析。方法选取本院自2011年12月~2012年12月收治的80例多发伤患者作为观察组,并以患者创伤严重程度评分为依据将其分为≤15分组、16~25分组、26~35分组及≥36分组,同时选取同期收治的80例外科急诊患者作为对照组,对两组患者的血清肌酸激酶变化情况进行对比。结果观察组患者伤后自第1天起血清肌酸激酶水平明显高于对照组(P<0.05);且患者创伤程度越重患者的血清肌酸激酶水平增高程度越明显(P<0.05);伤后1~2天患者血清肌酸激酶水平达到峰值,之后逐渐下降;患者创伤程度越重血清肌酸激酶水平下降越缓慢。结论多发伤患者伴有明显的血清肌酸激酶改变现象,临床上可将其可作为判断多发伤患者全身软组织损伤程度的一项重要指标。
Objective To analyze the dynamic changes of serum creatine kinase in patients with multiple trauma. Methods Eighty cases of multiple traumatic patients admitted from December 2011 to December 2012 in our hospital were selected as the observation group. According to the severity of the patients’ trauma, the patients were divided into ≤15 group, 16 ~ 25 group, 26 ~ 35 group Grouping and ≥36 grouping, at the same time select the same period 80 cases of surgical emergency patients as a control group, the two groups of patients with changes in serum creatine kinase were compared. Results The serum creatine kinase level in the observation group was significantly higher than that in the control group (P <0.05), and the more severe the degree of trauma patients was, the more the serum creatine kinase level was increased (P <0.05). Serum creatine kinase levels peaked 1 to 2 days after injury, and then gradually decreased; the more traumatic patients, the more the serum creatine kinase level decreased more slowly. Conclusions The patients with multiple traumatic injury are accompanied by obvious changes of serum creatine kinase, which can be used clinically as an important index to judge the extent of systemic soft tissue injury in multiple trauma patients.