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目的了解济宁市农村全人群乙肝感染情况及乙肝疫苗的免疫效果,为制订我市具体的乙肝防治措施提供科学依据。方法随机选择济宁市两村庄,按分层抽样的方法调查636人,并采集血标本,检测乙肝感染情况和抗体水平。结果济宁市农村乙型病毒性肝炎表面抗原携带率已降至较低水平(1.57%),乙肝表面抗体阳性率1~4岁年龄组(75.47%)高于5~14岁年龄组(59.09%),高于15~59岁年龄组(31.33%)。结论乙肝疫苗纳入免疫规划管理后大大提高了全市儿童人群乙肝表面抗体的阳性率,起到了很好的保护效果。
Objective To understand the hepatitis B infection status of hepatitis B vaccine and the immunization effect of hepatitis B vaccine in rural areas of Jining City, so as to provide a scientific basis for formulating the specific hepatitis B prevention and control measures in our city. Methods Two villages in Jining City were selected at random, 636 were surveyed by stratified sampling method, and blood samples were collected to detect hepatitis B infection and antibody levels. Results The prevalence of surface antigen of hepatitis B virus in rural areas of Jining City dropped to a low level (1.57%). The positive rate of hepatitis B surface antibody in patients aged 1 to 4 years (75.47%) was higher than that of patients in 5-14 age group (59.09% ), Higher than the 15 to 59 age group (31.33%). Conclusion Hepatitis B vaccine into the immunization program management greatly increased the positive rate of hepatitis B surface antibody in children in the whole city and played a very good protective effect.