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目的调查吉林省一家综合医院新诊断成人癫痫患者的自然现状,为开展地区癫痫防治工作提供依据。方法收集2016年10月-2017年2月就诊于吉林大学第一医院癫痫专病门诊新诊断的成人癫痫患者的自然资料及病史资料,并治疗随访6个月,进行统计学分析。结果新诊断成人癫痫患者81例,男:女=1.4:1;首次治疗时病程平均45.8个月,中位数18个月73例(90.1%)为局灶性起源,长程视频脑电图检查阳性率达91.3%;病因不明占69.1%;12例(14.8%)患者头部核磁共振检查提示海马硬化;48例(59.3%)患者有轻度认知功能下降;30例(37%)患者治疗依从性差。结论吉林大学第一医院新诊断成人癫痫患者多为局灶性起源,首次治疗均延迟,半数以上患者有轻度认知功能的下降,且治疗依从性差。
Objective To investigate the natural status of newly diagnosed adults with epilepsy in a general hospital in Jilin Province and provide evidence for the prevention and treatment of epilepsy in the area. Methods From October 2016 to February 2017, the natural and history data of newly diagnosed adult patients with epilepsy at the First Affiliated Hospital of Jilin University were collected. The patients were followed up for 6 months for statistical analysis. Results There were 81 newly diagnosed adults with epilepsy, male: female = 1.4: 1. The mean duration of the first treatment was 45.8 months, and the median of 18 months was 73 (90.1%). The long-term video EEG The positive rate was 91.3%; the etiology was unknown (69.1%); the head MRI of the 12 patients (14.8%) showed hippocampal sclerosis; 48 (59.3%) patients had mild cognitive decline; Poor treatment compliance. Conclusions The newly diagnosed adults with epilepsy in First Hospital of Jilin University were mostly of focal origin. The first treatment was delayed. More than half of patients had mild cognitive decline, and the treatment compliance was poor.