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乙型肝炎病毒(HBV)仅感染人和黑猩猩。该病毒也在土拨鼠、地松鼠、北京鸭中检出,这些病毒总称为嗜肝DNA病毒,为直径42nm的病毒颗粒,其主要成分为外膜蛋白的表面抗原(HBsAg)病毒DNA及形成复合体的核心抗原(HBcAg/HBeAg)。病毒DNA由正链和负链的双股环状DNA分子组成。负链全长约3.2kb,其5′末端结合着一个蛋白分子。正链长度为负链的50～100％。两条链分别由11个碱基序列同向重复相连(DR1和DR2),具有一个约220个
Hepatitis B virus (HBV) infects only humans and chimpanzees. The virus is also detected in groundhog, ground squirrel, Beijing duck, these viruses are collectively referred to as hepadnavirus, 42nm diameter virus particles, the main component of the outer membrane protein surface antigen (HBsAg) virus DNA and the formation of Complex core antigen (HBcAg / HBeAg). The viral DNA consists of double-stranded circular DNA molecules of positive and negative chains. The minus strand is about 3.2 kb in length and has a protein molecule attached to its 5 ’end. Positive chain length of 50 to 100% of the negative chain. The two strands are connected in the same direction by 11 base sequences (DR1 and DR2), respectively, and have about 220