目的 分析胰十二指肠切除术后并发症及防治方法。方法 通过我院10年之间行胰十二指肠切除术病人132例,分析其术后各种并发症。结果 132例中,21例出现术后并发症,发生率15.9％。包括胰瘘4例,胆瘘2例,胃肠吻合口瘘1例,腹腔感染5例,消化道出血4例,腹腔出血2例等。结论 本文对防止胰瘘、胆瘘、腹腔出血、消化道出血及腹腔感染提出了具体防治措施。 Objective To analyze the postoperative complications and prevention methods of pancreaticoduodenectomy. Methods 132 patients undergoing pancreaticoduodenectomy for 10 years in our hospital were analyzed for postoperative complications. Results Among 132 cases, 21 cases had postoperative complications with an incidence of 15.9%. Including 4 cases of pancreatic fistula, 2 cases of biliary fistula, 1 case of intestinal anastomotic fistula, 5 cases of abdominal infection, 4 cases of gastrointestinal bleeding, 2 cases of abdominal bleeding. Conclusion This article presents specific prevention and treatment measures for prevention of pancreatic fistula, biliary fistula, abdominal hemorrhage, gastrointestinal hemorrhage and abdominal infection.