论文部分内容阅读
目的对比PET/CT不同阈值勾画方法及MRI/CT融合图像勾画方法示鼻咽癌肿瘤体积的差异,探讨PET/CT勾画鼻咽癌肿瘤靶区(GTV_()最佳方法。方法选择2012年1月至2014年1月蚌埠医学院第一附属医院50例病理组织学确诊为鼻咽癌的患者入组。在MRI/CT融合图像上勾画获得GTV_(MRI/CT),在PET/CT融合图像上以SUV值为2.5自动勾画得到GTV_(PET2.5),以40%最大标准摄取值自动勾画得到GTV_(PET40%,以50%最大标准摄取值自动勾画得到GTV_(PET50%。线性回归分析各体积之间相关性。结果 GTV_(MRI/CT),GTV_(PET2.5),GTV_(PET40%),GTV_(PET50%)分别为(23.50±15.44)cm~3,(30.72±17.72)cm~3,(23.41±15.08)cm~3,(19.12±13.26)cm~3。GTV_(PET2.5)大于GTV_(PET40%)和GTV_(MRI/CT(P<0.05)),GTV_(PET40%)大于GTV_(PET50%(P<0.05)),GTV_(PET50%小于GTV_(MRI/CT(P<0.05),GTV_(PET40%与GTV_(MRI/CT相比差异无统计学意义(P>0.05)。GTV_(MRI/CT与GTV_(PET2.5)、GTV_(PET40%)、GTV_(PET50%)密切相关(r=0.978、0.991、0.990,P<0.05)。结论采用40%最大标准摄取值自动勾画肿瘤靶区是临床较佳选择。
OBJECTIVE: To compare the difference of tumor volume between nasopharyngeal carcinoma and PET / CT, and to explore the best method of PET / CT for delineating the target of GTV_ (.) From January to January 2014, 50 patients diagnosed as nasopharyngeal carcinoma by pathology in the First Affiliated Hospital of Bengbu Medical College were enrolled in the study.GTV_ (MRI / CT) was sketched on MRI / CT fusion images, GTV_ (PET2.5) was automatically delineated with a SUV value of 2.5, and GTV_ (PET40%) was automatically delineated with a 40% maximum standard intake value, and GTV_ (PET50% was automatically delineated with a maximum standard intake value of 50% (P <0.05) .Conclusion The correlation between volume of GTV_ (MRI / CT), GTV_ (PET2.5), GTV_ (PET40%) and GTV_ (PET50%) were (23.50 ± 15.44) cm3 and (30.72 ± 17.72) (23.41 ± 15.08) cm ~ 3, (19.12 ± 13.26) cm ~ 3.GTV_ (PET2.5) was greater than GTV_ (PET40%) and GTV_ (MRI / CT (P <0.05), GTV (PET50% less than GTV_ (MRI / CT), GTV_ (PET40% vs GTV_ (MRI / CT) .GTV_ (MRI / CT was closely related to GTV_ (PET2.5), GTV_ (PET40%) and GTV_ (PET50%) (r = 0.978, 0.99 1, 0.990, P <0.05) .Conclusion It is a better clinical choice to automatically delineate the tumor target area with 40% of maximal standard intake value.