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目的:探讨阴囊Paget病的临床特点、诊断及治疗方法。方法:回顾性分析26例阴囊Paget病的临床资料,并进行随访。本组Ray分期A1期13例,A2期8例,B期5例;手术治疗25例(19例行根治性病灶切除术,6例行病灶扩大切除+股部带蒂皮瓣修补术,5例腹股沟淋巴结转移者行单侧或双侧腹股沟淋巴结清扫术),实施放、化疗1例。结果:术后均经病理学检查确诊。术后24例获随访,随访时间3个月~15年,平均4年。2例分别于术后5个月、1年局部复发,均再次手术治愈。1例术后2年死于多发骨转移。其余无局部复发及转移。结论:阴囊Paget病临床少见,易误诊为阴囊湿疹、皮炎等;对可疑阴囊Paget病者应尽早活检确诊;病灶根治切除术是首选治疗方法,早期治疗预后较好。
Objective: To investigate the clinical features, diagnosis and treatment of Paget’s disease in the scrotum. Methods: A retrospective analysis of 26 cases of scrotum Paget disease clinical data and follow-up. In this group, 13 patients were divided into stage A1, stage A2, stage 8, stage B, stage 5, stage B, stage 25, stage B, Cases of inguinal lymph node metastasis were unilateral or bilateral inguinal lymphadenectomy), the implementation of radiotherapy and chemotherapy in 1 case. Results: Postoperative pathological examination confirmed. 24 cases were followed up for 3 months to 15 years with an average of 4 years. 2 cases were at 5 months after surgery, 1 year local recurrence, were re-operative cure. One patient died of multiple bone metastases 2 years after operation. The rest without local recurrence and metastasis. Conclusion: Scrotum Paget disease is rare and easily misdiagnosed as scrotal eczema and dermatitis. Biopsy of patients with suspected scrotum Paget should be diagnosed as soon as possible. Radical resection is the preferred treatment and the prognosis of early treatment is good.