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目的:研究炼化医院2011-2013年抗菌药物应用状况,为规范合理用药提供参考。方法:采用系统抽样的方法,在该院2011-2013年收治的患者中按年抽取243例进行回顾性分析。将病例信息进行汇总分析,对3年来抗菌药物使用人数、用途及联合用药的例数进行统计。统计患者药物使用频度(DDDS)、限定日费用(DDC),计算抗菌药物花费占住院费用的比重。结果:在243例患者中抗菌药物的使用率达到了75.72%,其中使用抗菌药物用于预防的人数有100人,大于为了治疗而使用抗菌药物的人数84人。单独使用抗菌药物治疗的病例在治疗病例中占到了88.59%。在患者的费用方面,药物费用占总住院费用的比例为31.36%(612 562/1 953 182元)抗菌药物花费费用占药物费用的比例为19.27%(118 047/612 562元),药物费用占住院费用,抗菌费用占药物费用的比重都比较合理。头孢类抗菌素无论还是DDDS、DDC排名都比较靠前,头孢哌酮舒巴坦、头孢替安、头孢唑肟、头孢硫脒的DUI指数大于1,医院存在着用药不合理的现象。结论:2011-2013年间抗菌类药物使用存在弊端,必须加强对抗菌类药物合理应用的管理。
Objective: To study the status of antibacterials application in Refining and Purification Hospital from 2011 to 2013, and to provide reference for standardizing rational drug use. Methods: A systematic sampling method was used to retrospectively analyze 243 consecutive patients from 2011 to 2013 in our hospital. The case information were pooled and analyzed. The number of antibacterials used, their use and the number of combined medication were counted in the past three years. Statistics of patients with drug use frequency (DDDS), the definition of daily expenses (DDC), calculate the proportion of antimicrobial drugs accounting for hospitalization costs. Results: In 243 patients, the usage of antibacterials reached 75.72%. Among them, there were 100 people who used antibacterials for prevention and 84 people who used antibacterials for treatment. The cases treated with antibiotics alone accounted for 88.59% of the treated cases. In terms of patients’ costs, the proportion of drug expenses to total hospitalization expenses was 31.36% (612 562/1 953 182 yuan). The cost of antimicrobial drugs accounted for 19.27% (118 047/612 562 yuan) of drugs, and the cost of medicines accounted for Hospital expenses, antibacterial costs accounted for the proportion of drug costs are more reasonable. Cephalosporin antibiotics whether DDDS or DDC rankings are more advanced, cefoperazone sulbactam, cefotiam, ceftizoxime, cefathiamidine DUI index greater than 1, the hospital there is irrational medication. Conclusion: The use of antimicrobial drugs has disadvantages in 2011-2013, and the rational management of antimicrobial drugs must be strengthened.