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目的比较乳腺癌患者行保乳治疗与改良根治术的临床疗效。方法选取2008年10月—2010年10月福清市医院收治的乳腺癌患者64例,按照分层法分为试验组和对照组,各32例。试验组行保乳手术,对照组行改良根治术,比较两组患者临床疗效、美容效果及并发症发生情况。结果两组患者复发率、远处转移率及生存率比较,差异无统计学意义(P>0.05)。试验组临床优良率为93.75%,高于对照组的75.00%,差异有统计学意义(P<0.05)。两组患者并发症发生率比较,差异有统计学意义(P<0.05)。结论保乳治疗在改善乳腺癌患者预后方面优于改良根治术,安全性高,疗效无差异。
Objective To compare the clinical efficacy of breast-conserving therapy and modified radical mastectomy in patients with breast cancer. Methods Sixty-four breast cancer patients who were treated in Fuqing Hospital from October 2008 to October 2010 were divided into experimental group and control group according to the stratified method, with 32 cases in each group. The experimental group underwent breast-conserving surgery and the control group underwent modified radical mastectomy. The clinical effects, cosmetic effects and complications of the two groups were compared. Results There were no significant differences in recurrence rate, distant metastasis rate and survival rate between the two groups (P> 0.05). The clinical excellent and good rate of the experimental group was 93.75%, which was higher than that of the control group (75.00%), the difference was statistically significant (P <0.05). The complication rates of the two groups were statistically significant (P <0.05). Conclusion Breast-conserving therapy is better than modified radical mastectomy in improving the prognosis of patients with breast cancer, with high safety and no difference in curative effect.