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目的探讨对伴血脂异常的2型糖尿病(T2DM)患者的治疗方法。方法格华止联合甘精胰岛素(IG)睡前注射20例(IG组)和早晚餐前两次皮下注射诺和灵30R30例(Novolin30R组)。结果 12周后两组血糖、糖化血红蛋白明显下降,IG组低血糖发生较少,体重不增加,血胆固醇、甘油三酯明显下降,C肽升高显著。结论格华止联合甘精胰岛素有较好疗效,不仅可改善胰岛β细胞功能,还有调脂和心血管保护作用。
Objective To investigate the treatment of type 2 diabetes mellitus (T2DM) patients with dyslipidemia. Methods GAVA combined with insulin glargine (IG) at bedtime in 20 patients (IG group) and twice-daily morning and evening subcutaneous injection of Novolin 30R30 (Novolin30R group). Results After 12 weeks, the levels of blood glucose and HbA1c in the two groups decreased significantly. The incidence of hypoglycemia in IG group was less, body weight did not increase, blood cholesterol and triglyceride decreased significantly, and C peptide increased significantly. Conclusion GVT combined with insulin glargine has a good effect, not only can improve pancreatic β-cell function, but also lipid-lowering and cardiovascular protection.