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目的探讨2型糖尿病患者门诊自我注射预混胰岛素后血糖控制的有效性。方法选取2015年3月—2016年3月86例锦州医科大学附属第一医院的2型糖尿病初期患者为研究对象,采用双盲法对患者进行随机分组,分为常规组和治疗组,每组43例。常规组注射胰岛素,治疗组注射预混胰岛素。观察患者血糖控制时胰岛素使用用量、血糖控制时间及治疗总费用情况,检测用药前后患者血糖水平改善情况,记录两组疗程不良反应的发生情况。结果治疗组较常规组血糖控制用时少、胰岛素使用量小、治疗总费用少,两组比较差异有统计学意义(P<0.05);入院时两组血糖指标比较差异无统计学意义(P>0.05),用药后治疗组血糖水平降低效果优于常规组(P<0.05);治疗组不良反应发生率为2.32%,低于常规组的9.33%,两组比较差异有统计学意义(P<0.05)。结论临床上对2型糖尿病初期患者治疗时采用患者门诊自我注射预混胰岛素,治疗效果显著且不良反应少。
Objective To investigate the effectiveness of glycemic control in patients with type 2 diabetes mellitus after self-injection of premixed insulin. Methods From March 2015 to March 2016, 86 patients with type 2 diabetes in the First Affiliated Hospital of Jinzhou Medical University were enrolled. Patients were randomly divided into two groups: control group and treatment group 43 cases. In the conventional group, insulin was injected and in the treatment group, premixed insulin was injected. Observe the use of insulin in patients with glycemic control, blood glucose control time and the total cost of treatment, test patients before and after treatment to improve blood glucose levels, recording the incidence of adverse reactions in both groups. Results Compared with the control group, the treatment group had less blood glucose control, less insulin dosage, and less total treatment cost. There was significant difference between the two groups (P <0.05). There was no significant difference in blood glucose between the two groups at admission (P> 0.05). After treatment, the blood sugar level of the treatment group was lower than that of the conventional group (P <0.05). The incidence of adverse reactions in the treatment group was 2.32%, which was lower than 9.33% in the conventional group, with significant difference between the two groups (P < 0.05). Conclusions Clinically, patients with type 2 diabetes treated with self-injection of premixed insulin at outpatient treatment have significant curative effect and few adverse reactions.