壶腹周围癌是发生于胰头、胆总管末端、壶腹部及十二指肠乳头的恶性肿瘤，其发病率近年来呈上升趋势，由于多种原因，壶腹周围癌的早期诊断十分困难，大多数患者就诊时已属中、晚期，失去了手术切除的机会，预后极差。我院１９８６年１月～１９９８年１２月经剖腹探查和病理证 Periampullary cancer is a malignant tumor that occurs in the head of the pancreas, the end of the common bile duct, the ampulla, and the duodenal papilla. Its incidence has been on the rise in recent years. Early diagnosis of periampullary cancer is difficult because of many reasons. Most of the patients have been in the middle and late stages of treatment, and they have lost the chance of surgical resection. The prognosis is extremely poor. From January 1986 to December 1998 in our hospital by laparotomy and pathology