精原干细胞能通过自增殖不断地自我更新,形成不同发育阶段的生精细胞并维持其正常数目。Broil基因属于Polycomb家族,最近发现它对造血干细胞、白血病干细胞、神经干细胞等自增殖有调控作用。我们用自制的BMI1多克隆抗体,通过免疫荧光技术定位该基因在小鼠睾丸组织中的表达,并用 Spermatogonial stem cells can continuously self-renew through self-proliferation to form spermatogenic cells of different developmental stages and maintain their normal numbers. The Broil gene belongs to the Polycomb family and has recently been found to regulate the proliferation of hematopoietic stem cells, leukemia stem cells, and neural stem cells. We use the homemade BMI1 polyclonal antibody, the expression of the gene in mouse testis by immunofluorescence technique and use