论文部分内容阅读
Ⅰ型糖尿病是由T细胞介导自身免疫性疾病,由胰岛β细胞免疫破坏所致.其基因免疫治疗主要包括诱导免疫耐受、改变抗原提呈细胞的功能及活性、改变免疫调节细胞因子、干扰协同刺激信号和调节细胞凋亡.
Type I diabetes is mediated by T cell autoimmune disease, which is caused by the destruction of islet beta cell immunity, which includes inducing immune tolerance, altering the function and activity of antigen presenting cells, changing immunomodulatory cytokines, Interfere with costimulatory signals and regulate apoptosis.