ACTIVIN相关论文
第一章 XTbx6 在体节发生过程中的作用需要较低活性的 BMP-4 信号T-box 基因属于一类转录调控因子家族,在胚胎的不同阶段,多种的器......
多能干细胞(pluripotent stem cells,PSCs)包括胚胎干细胞和诱导多能干细胞。由于PSCs具有无限增殖和分化成不同三胚层细胞的能力,使......
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BACKGROUND Hereditary hemorrhagic telangiectasia(HHT)is a rare autosomal dominant genetic disease.Very few patients suff......
Regulation of activin A in cell proliferation and hormone secretion by human normal trophoblast cell
Regulation of activin A in cell proliferation as well as hCG and progesterone secretion was investigated using primary c......
目前,卵巢癌主要的血清标记物是CA125,最近几个研究小组的报道提示血清抑制素(inhibin)浓度可作为一种有用的标记物,以补充CA125......
BMPs属于转化生长因子-β超家族,在介导细胞增殖、凋亡、迁移、分化等方面发挥了重要作用。BMPs异常表达、紊乱在肿瘤发生、发展过......
新近的研究证明,遗传性出血性毛细血管扩张症(hereditary hemorrhagic telangiectasia, HHT)发病的分子机制涉及到转化生长因子β(......
原始生殖细胞(primordial germ cells,PGCs)是一类具有分化潜能的生殖细胞。为了检测激活素A(activin A)对鸡胚血液PGCs体外存活和......
Hereditary hemorrhagic telangiectasia(HHT)is a rare autosomal-dominantly inherited disease that occurs in approximately ......
AIM: To identify genes responsive to apoptosis in HL-60 cells treated by homoharringtonine. METHODS: cDNA microarray tec......
Cripto为表皮生长因子 (EGF)CFC家族的成员 ,基本结构包含信号肽、一个EGF结构域、一个CFC结构域和 -COOH疏水末端。Cripto可作为......
转化生长因子β(transforminggrowthfactors-β,TGF-β)是一类多功能的多肽类生长因子,主要包括TGF-βs、激活素(activin)/抑制素(......
目的 研究血清孕酮(P)、β-人绒毛膜促性腺激素(β-HCG)及血清激活素A(ACTA)联合检测对早期异位妊娠的诊断价值.方法 回顾性分析住......
此项研究根据血清中抑制素(inhibin)和激活素(activin)的水平与肿瘤参数,包括:肿瘤分期、病理分级,患者年龄之间的关系阐明术前血......
Smad4/DPC4基因是新近被鉴定的一个肿瘤抑制基因,定位于染色体18q21.1。其编码的Smad4/DPC4蛋白是细胞生长TGF-β受体调控途径中的重要......
治疗广泛性牙周炎34例,年龄30~55岁。治疗前、后进行免疫学检查:T淋巴细胞数,辅助性和抑制性T细胞数、B淋巴细胞效、未成熟的淋巴......
Presynaptic inhibition of nociceptive neurotransmission by somatosensory neuron-secreted suppressors
Noxious stimuli cause pain by activating cutaneous nociceptors.The Aδ-and C-fibers of dorsal root ganglion(DRG) neurons......
AIM To examine the expression of activin A, amember of the transforming growth factor (TGF-β) superfamily, recently ha......
目的:观察百草枯对PC12细胞的活化素不同亚基和受体表达的影响。方法:将百草枯加入体外培养的PC12细胞中,用RTPCR法检测细胞的活化......
目的 观察四氯化碳 (CCl4 )诱导实验性肝纤维化模型大鼠肝纤维化形成过程中激活素(activin ,ACT)A的表达。方法 40 %CCl4 皮下......
Objective To evaluate the variation of serum activin A level in liver cirrhotic patients.Methods 83 liver cirrhotic pat......
转化生长因子(transforming growth factor,TGF-β)超家族包括TGF-β1、激活素(activin)、骨形态发生蛋白(bone morphoge-netic pr......
Down-regulation of transforming growth factor β1/activin receptor-like kinase 1 pathway gene express
AIM: To investigate the effect of herbal compound 861 (Cpd861) on the transforming growth factor-β1 (TGFβ1)/ activin r......
The effects of transforming growth factor-β1 (TGF-β1) are currently controversial. Whether TGF-β1 promotes or inhibit......
Activin A maintains cerebral cortex neuronal survival and increases voltage-gated Na~+ neuronal curr
Activin A,which was first described in 1986,has been shown to maintain hippocampal neuronal survival.Activin A increases......
目的探讨激活素A(activin A,ACTA)在估价慢性乙型病毒性肝炎程度中的作用。方法采用酶联免疫(ELISA)法测定118例患者血清ACTA含量......
阜阳市局 £4a 局长——_MINtkMMtgj’#lnH$B——q.M——D收束志不他只邀狲位J则【科校为先导推动地租工作.B为广为戳民U用凶盼引眯B.......
Hes1,an important gene for activation of hepatic stellate cells,is regulated by Notch1 and TGF-β/BMP
AIM:To determine the role of Notch1 and Hes1 in regulating the activation of hepatic stellate cells(HSCs) and whether He......
近几年来,关于性腺对垂体促性腺激素的反馈调节作用,人们主要将注意力放在抑制素(inhibin)上。nhibin 是一种糖蛋白,可特异抑制腺......
抑制素(inhibin)和激活素(activin)是2种主要由性腺分泌的肽类激素,因分别能抑制和促进体外培养的垂体促性腺细胞释放促卵泡激素(f......
AIM: To investigate the regulation of activin receptor-interacting protein 2 (ARIP2) expression and its possible relatio......
抑制素和活化素(activin)均是蛋白类激素,具有共同的β亚单位,可调节胰岛素分泌、红细胞生成及垂体前叶的几种细胞。近来发现蛋白......
Regulation of activin A in cell proliferation and hormone secretion by human normal trophoblast cell
Regulation of activin A in cell proliferation as well as hCG and progesterone secretion was investigated using primary ......
年长育龄妇女以血FSH上升为其内分泌特点,此时月经周期和排卵功能仍可正常,卵泡期可缩短2~7天,早卵泡期血雌二醇(E_2)及尿E_2代谢......
Smad蛋白家族是近年来发现的新的细胞内信号转导蛋白 ,哺乳类中共发现了有 8种不同的Smad蛋白 ,可分为 3个不同的亚族 :R Smad、Co......
卵巢内激活素(activin,ACT)/抑制素(inhibin,INH)系统主要由ACT、INH和与ACT和INH调节有关的因子,如卵泡抑素(follistatin,FS)、Sm......
Macrophages play critical roles in innate immune and acquired immune via secreting pro-inflammatory mediators, phagocyto......
本研究旨在探讨活化素(activin)对大鼠垂体GH3细胞中人生长激素(hGH)基因启动子活性的影响及其可能的调节机制。采用荧光素酶报告......
背景:激活素作为卵巢内调控分子,对卵巢卵泡发育起着重要作用。目的:探索表皮生长因子在激活素基因表达过程中所起的重要作用以及......
有关抑制素(inhibin)的研究进行了近八十年的时间,但进展十分缓慢,中间一段时间几乎停止,关键在于它的作用机理(受体的研究)没有弄......
Stem cells are a population of cells that has infinite or long-term self-renewal ability and can produce various kinds o......
目的探讨激活素受体相互作用蛋白1(activin receptor-interaction protein 1,ARIP1)和ARIP2在小鼠脑神经细胞中的共表达。方法 RT-......
近年来研究证实,青光眼病人的细胞免疫参数明显降低,这很可能是手术或药物治疗后,眼压虽正常,但视功能仍继续下降的原因之一。基......
目的探讨温肾养血方对无排卵大鼠抑制素—激活素—卵泡抑素(inhibin-activin-follistatin,INH-ACT-FS)系统和性腺激素水平的影响。......
Tripartite motif 33(TRIM33), a member of the transcription intermediate factor 1(TIF1) family of transcription cofactors......
Hepatocellular carcinoma(HCC)is the most common primary liver cancer and accounts for 80%-90% of this class of malignanc......