HEPCIDIN相关论文
目的 对斑马鱼Hepcidin-2基因结构进行生物信息学分析,并设计优化其抗菌活性.方法 选取斑马鱼Hepcidin-2作为目的基因,通过Tblastn......
抗菌肽（antimicrobial peptides）是一种具有广谱抗菌活性的小分子多肽，目前已发现了大约1900种，几乎存在于所有的物种中。这种多肽具有......
目的 探讨当归多糖(ASP)、香菇多糖(LEP)和蒲公英多糖(DP)3种中药多糖体外抑制肝癌HepG2细胞增殖的作用及其相关机制.方法 体外培......
Catfish hepcidin gene is expressed in a wide range of tissues and exhibits tissue-specific upregulat
Antimicrobial peptides (AMPs) are important components of the host innate immuneresponse against microbial invasion. ......
Cloning and expression of two hepcidin genes from grouper (Epinephelus tauvina) and their antipathog
Hepcidin gene is widely expressed in various fish, suggesting that this antimicrobial peptide is a very important compon......
Objective Hepcidin is a key iron-regulatory hormone.Growth Differentiation Factor 15(GDF-15)is identified as one of medi......
目的：铁调节蛋白(hepcidin)，是一种主要在肝脏中表达的多肽激素，既能抑菌杀菌，也可以调节铁的吸收、利用及储存的平衡，达到铁的稳态。已......
目的 随着我国进入老龄化社会,老年贫血将成为一个重要的公共卫生问题,应引起我们足够的重视.Hepcidin 是近年来发现的铁代谢的关......
Increased hepcidin in transferrin-treated thalassemic mice correlates with increased liver BMP2 expr
Iron overload results in significant morbidity and mortality in β-thalassemic patients.Insufficient hepcidin is implica......
目的：铁是人体必须的微量元素之一。妊娠期维持铁代谢的稳态至关重要。铁调素-Hepcidin,已被确定为铁平衡的关键调节激素目前有关妊......
目的:探讨心理应激影响机体铁分布的分子调节机制以及IL-6-hepc轴在心理应激大鼠铁代谢紊乱中的作用.方法采用Communication Box S......
铁是人体最丰富的必需微量元素之一，广泛参与体内生理过程。但是过量的铁可诱发自由基生成从而造成机体损伤。在酒精性肝病发病机制......
Osteoporosis has until now been considered to be a disease associated with abnormal calcium metabolism.However, an incre......
Serum Hepcidin Predicts Uremic Accelerated Atherosclerosis in Chronic Hemodialysis Patients with Dia
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<strong>Objective:</strong> To preliminary study the significance of low molecular weight heparin (LMWH) in the treatmen......
遗传性血色素沉积症是一种较为常见的遗传性疾病，其主要相关的致病基因有HFE、HJV、TfR2、FPN1、FTH1和HAMP等.HJV作为BMP的共......
Expression of hepcidin at the choroid plexus in normal aging rats is associated with IL-6Stat3 signa
Accumulating evidence has revealed that brain iron concentrations increase with aging, and the choroid plexus may be......
Background: Imbalance of iron hemostasis is the feature of hepatocyte damage and liver diseases,including hemochromatosi......
A number of studies have shown that many of the mechanisms involved in the regulation of iron transport and utilizat......
It has been proved that iron progressively accumulates in the brain with age.Calorie restriction (CR) may allay many......
目的研究维生素A(VA)缺乏时大鼠铁营养状况的变化,从分子水平探讨VA缺乏对大鼠铁代谢的影响。方法 16只成年健康雄性SD大鼠,随机分......
近年来,铁代谢及其调节机制的研究取得了一系列突破性进展,有力地促进了遗传性血色病(hereditary he-mochromatosis,HH)的分子机制......
Objective: Iron deficiency is a common complication in patients with polycythemia vera (PV). Hepcidin is a principal reg......
Hepcidin is a peptide hormone with both paracrine and endocrine functions that help in maintaining body iron stores.Type......
目的:探讨血清铁调素(Hepcidin)在老年人群缺铁性贫血(IDA)和慢性病贫血(ACD)中的应用价值。方法:选择老年IDA患者32例,老年ACD患......
术后认知功能障碍(postoperative congnitive dysfunction,POCD)是老年人麻醉手术的研究热点,表现为近期记忆、思维集中能力、语言......
跨膜丝氨酸蛋白酶6 (transmenbrane serine proteases 6,TMPRSS6) 也 称matriptase-2,属于Ⅱ型跨膜型丝氨酸蛋白激酶家族( type ......
目的 探讨Hepcidin对脓毒症患者危重程度及近期临床预后的评估价值.方法 采用观察性研究方法,纳入在2016-03 ～2016-10间,上海市浦东......
目的：探讨铁调素对成骨细胞铁代谢指标、骨代谢指标的影响和相互关系。方法成骨细胞（ hFOB1.19）培养3 d后，使用逆转录-聚合酶链反应（RT-......
铁调素是一种肝脏分泌的小分子肽，其对铁代谢调节起负调控作用。铁的缺乏与过载会导致多种疾病，但机体本身缺乏对铁排泄的调控机制，所......
目的在机体,铁调素(Hepcidin)、膜转铁蛋白(FPN)、二价金属转运蛋白1(DMT1)、十二指肠色素b(DCYTB)是调节铁代谢的重要通道蛋白;本......
慢性病贫血(ACD)是一种常见的临床并发症,可加剧原发疾病对身体的损伤,对原发疾病的治疗及预后带来不利影响.其发病机制包括促红细......
目的探讨维持性血液透析（MHD）患者血清铁调素水平与铁和矿物质代谢的相关性。方法选取MHD患者75例，应用酶联免疫吸附双抗体夹心法检测......
Objective: To produce fluorescent tagged recombinant erythroferrone protein (ERFE_eGFP) for laboratory investigations. M......
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AIM: To examine body fluids such as ascitic fluid (AF), saliva, bile and pleural effusions for the presence of hepcidin ......
Applied Value of Monitoring Serum Hepcidin in Differential Diagnosis of Infection versus Tumor Fever
The applied value of serum hepcidin in differential diagnosis of infection fevers versus tumor fevers was explored.A tot......
目的 观察多烯磷脂酰胆碱对酒精性肝病大鼠铁稳态的影响,并对其作用机制作初步的探讨.方法 将30只大鼠随机分为对照组、模型组和治......
目的 探讨再生障碍性贫血(AA)患者血清hepcidin的表达及其与血清铁蛋白(SF)间的关系.方法 用ELISA、放射免疫法测定45例AA患者(AA......
Antimicrobial peptide hepcidin contributes to host defense of Centropristis striata against Vibrio h
Hepcidins are small cysteine-rich antimicrobial peptides that play a vital role in immunity against pathogen invasion.He......
