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AIM:rAAV mediated endostatin gene therapy has beenexamined as a new method for treating cancer.However,a sustained and ......
Triterpenoid of avocado (Persea americana) seed and its cytotoxic activity toward breast MCF-7 and l
Objective:To determine the structure of triterpenoid isolated from avocado seeds and the cytotoxic effect on MCF-7 and H......
Electrochemical investigation on the interaction of benzene sulfonyl 5-fluorouracil derivatives with
The interaction of double-stranded(ds) and G-quadruplex(G4) DNA with sulfonyl 5-fluorouracil derivatives(5-fluoro-1-(ary......
Pharmacodynamics of Paclitaxel Long-circulating Thermo-sensitive Liposome in Mice Bearing Lewis Lung
[Objective] To investigate the tumor inhibition effects of paclitaxel long-circulating thermo-sensitive liposome( PLTL) ......
用量子化学密度泛函理论(DFT),并结合导体极化连续模型(CPCM)研究了具有潜在抗肿瘤活性的"Keppier型"钌配合物trans-[Ru~ⅢCl_4(2-......
目的:用体外细胞培养法观察山梨猕猴桃根提取物乙醇浸膏正丁醇溶解部分对肿瘤细胞株生长的抑制作用.方法:采用MTT法、细胞集落形成......
报道了以3-三氟苯胺为起始原料进行氟他胺合成的工艺改进方法,即,碳酸氢风作为吸氯化氢剂的条件下,2-甲基丙酰氯与3-三氟甲基苯胺(Ⅰ)反应得到......
文章探讨陈年酱油的致突变性、抗癌活性以及肿瘤转移抑制能力。以经典Ames实验,MTT法和小鼠实验性肿瘤转移实验分别检测陈年酱油的......
地衣在许多国家中很早就被应用于医药事业,而近年来,其所含有的多种独特的化学物质,也正在引起各国化学家和药学家的广泛关注。本......
以6-(3,5-二甲基吡唑-1-基)-3-肼基均四嗪和芳醛为原料,经Schiff碱缩合和环合反应合成了6个新型的6-芳基-3-(3,5-二甲基吡唑-1-基)[1,2......
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采用人工合成的方法研究绿蝇防御素(phormicin A)对细菌及肿瘤细胞作用效果.实验结果发现,人工合成的绿蝇防御素可以在较低浓度下抑......
Inhibiting focal adhesion kinase:A potential target for enhancing therapeutic efficacy in colorectal
Focal adhesion kinase(FAK)is a major integrin-dependent tyrosine phosphorylated protein,recently,FAK association with co......
Synthesis, Structure and Biological Activities of a Novel Anionic Organotin (IV) Complex {[(p-ClC6H4
A novel anionic organotin(IV) complex {[(p-ClC6H4CH2)Sn(H2O)(Cl)2OCO-CH(O)CH(O)CO2Sn(H2O)(Cl)2(p-ClC6H4CH2)]?2(HNEt3)}(1......
2-Methoxystypandrone induces iNOS expression by H2O2-dependent JNK activation for multiple cancer ce
OBJECTIVE To investigate the mechanism of anticancer effect of 2-methoxystypandrone(2-MS),a natural naphthoquinone isola......
蓼属(Polygonum)的主要化学成分是黄酮类,醌类,苯丙素类和萜类类化合物,具有抗癌,抗肿瘤,抗氧化,抗炎,镇痛,抗菌,杀虫等药理作用。......
对叶榕广泛分布在中国、印度、泰国、马来西亚等地,其药用历史悠久,具有催乳和通幔等功效,亦可治疗牛皮癣、糖尿病、肝炎等病症。对叶......
Annonaceous acetogenins, isolated from the Annonaceae plants, have been attracting worldwide attention in recent years d......