论文部分内容阅读
目的:检测研究IL-1β、IL-6、IL-8在需氧菌性阴道患者阴道分泌物中的表达,探讨其在需氧菌性阴道炎发病机制上的意义。方法:60例需氧菌性阴道炎患者分别留取阴道分泌物,IL-1β、IL-6、IL-8均采用双抗体夹心ELISA法检测,并与健康妇女阴道分泌物相比较。结果:需氧菌性患者阴道分泌物中IL-1β、IL-6、IL-8较正常健康妇女均有不同程度升高,差异有统计学意义(P<0.01)。结论:需氧菌性阴道患者阴道分泌物IL-1β、IL-6、IL-8的升高可能与需氧菌性阴道炎的发生机制有一定的关联,测定这些细胞因子水平对需氧菌性阴道炎的诊断及发病机制研究有一定的意义。
Objective: To study the expression of IL-1β, IL-6 and IL-8 in the vaginal secretions of aerobic vaginal patients and its significance in the pathogenesis of aerobic bacterial vaginosis. Methods: Sixty patients with vaginal discharge of aerobic vaginitis were collected vaginal discharge, IL-1β, IL-6, IL-8 were detected by sandwich ELISA, and compared with healthy women vaginal discharge. Results: Compared with normal healthy women, the levels of IL-1β, IL-6 and IL-8 in vaginal secretions of patients with aerobic bacteria increased to some extent, the difference was statistically significant (P <0.01). Conclusion: The increase of vaginal secretion IL-1β, IL-6 and IL-8 in aerobic vaginal patients may be related to the pathogenesis of aerobic bacterial vaginitis. The level of these cytokines in aerobic bacteria Sexual vaginitis diagnosis and pathogenesis of a certain significance.