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吸烟是人们公认的促使脑卒中发生的危险因素,然而吸烟对脑血管功能失调的作用机制尚未能得到明确的阐述。人们曾提出多种有关的推论,如血管收缩机制、凝血因子变化机制等。吸烟者脑卒中发生率增高与脑血液动力学短期的急剧改变有关。 研究对象和方法 研究采用经颅多普勒(TCD)检测大脑中动脉(MCA)在高碳酸血症时平均血流速度(MFV)的变化。研究对象为24名无脑血管疾病的健康吸烟者,并以24名性别、年龄相似的非吸烟者组成
Smoking is recognized as a risk factor for stroke, however, the mechanism of smoking on cerebrovascular dysfunction has not yet been clearly defined. People have put forward a variety of relevant inferences, such as vasoconstriction mechanism, coagulation factor change mechanism. The increased incidence of stroke in smokers has been associated with a drastic change in short-term cerebral hemodynamics. Subjects and Methods Subjects and Methods Transcranial Doppler (TCD) was used to measure mean blood flow velocity (MFV) changes in middle cerebral artery (MCA) during hypercapnia. The study population consisted of 24 healthy smokers without cerebrovascular disease and was composed of 24 non-smokers of similar sex and age