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Kupffer细胞是全身单核-吞噬细胞系统的重要组成部分,也是肝脏防御系统主要成员,在全身和肝脏疾病发生发展中起到重要作用.由龚建平教授领导的科研团队十多年来长期致力于Kupffer细胞与肝脏疾病关系的研究,在该课题上连续多次获得国家自然科学基金资助.到目前为止,对Kupffer细胞在感染与信号转导、移植与免疫耐受、脂质代谢以及肝癌发生发展等方面取得一定成绩,在国内外重要期刊上发表相关论文数十篇.在此基础上,我们组织纂写了本次Kupffer细胞专题焦点论坛,以期与国内外同行共同探讨研究Kupffer细胞的重要作用.
Kupffer cells are an important part of the systemic monocytic-phagocytic system and a major member of the liver defense system and play an important role in the development of systemic and liver diseases.The research team led by Prof. Gong Jianping has long been committed to Kupffer Cell and liver disease research, in this subject for many times by the National Natural Science Foundation of China.So far, Kupffer cells in infection and signal transduction, transplantation and immune tolerance, lipid metabolism and the occurrence of liver cancer development And made dozens of papers in important periodicals both at home and abroad.On this basis, our organization compiled the Kupffer cell thematic focus forum, with a view to discuss the important role of Kupffer cells together with domestic and foreign counterparts.