100例复治耐药病例,单耐H、S居首位,耐R者56.9％,呈上升趋势。耐2～3种药71％。100例肺切除标本中,空洞并支气管扩张(支扩)占28％、肺大疱占9％、霉菌感染占5％。认为:①复治病例耐2种以上药,尤以耐R者,继续化疗效果极差,应考虑手术。②有空洞支扩、肺大疱、霉菌感染应以手术为主。术后选用敏感药并多药联合化疗6～12个月,效果是满意的。 100 cases of retreatment-resistant cases, single resistance H, S first place, resistant to R 56.9%, an upward trend. Resistance to 2 to 3 kinds of drugs 71%. In 100 cases of lung resection, the cavity and bronchiectasis (branch expansion) accounted for 28%, bullae accounted for 9%, mold infection accounted for 5%. Refers to: ① retreatment cases resistant to more than two kinds of drugs, especially those resistant to R, continued poor chemotherapy, surgery should be considered. ② There are hollow expansion, bullae, mold infection should be based on surgery. Postoperative use of sensitive drugs and multi-drug combination chemotherapy 6 to 12 months, the effect is satisfactory.