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湖南医药工业研究所根据近几年来有关用瓜蒂吹鼻疗法、单味甜瓜蒂水浸出液治疗急慢性肝炎、肝硬化的报导,对于甜瓜蒂的化学成份进行了研究。从甜瓜蒂的醇提取物与水浸液中都找到了两种苦味结晶成分,经过精制鉴定其化学结构为葫芦素 B 及葫芦素E,并对葫芦素 B 进行了药理试验。为了深入研究葫芦素 B 对实验性急慢性肝损伤的防治作用,我们配合湖南医药工业研究所作了一系列实验研究,现报道于下。
The Institute of Hunan Pharmaceutical Industry has studied the chemical composition of melon pedicles based on the reports on the treatment of acute and chronic hepatitis and liver cirrhosis by using guti nasal aromatherapy and single-melon melon leaching solution in recent years. Two bitter crystal components were found in the alcohol extract and aqueous extract of melon guava. The chemical structures were identified as cucurbitacin B and cucurbitacin E. The cucurbitacin B was pharmacologically tested. In order to further study the role of cucurbitacin B in the prevention and treatment of experimental acute and chronic liver injury, we conducted a series of experimental studies with the Hunan Institute of Pharmaceutical Industry and reported it now.