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青光眼滤过术后疤痕形成是导致青光眼术后失败的主要原因，也是国内外专家一直在研究的课题。本文对适于行滤过手术的青光眼４５例５４眼，在小梁切除术中使用日本进口的丝裂霉素（ＭｉｔｏｍｙｃｉｎＣ）０．０５％浓度，使用１分钟。复发性青光眼、继发性青光眼使用１分钟×２次或２分钟×１次。术后经过３月－２年随访，９８％病例伴有白色滤枕，眼压得到控制，不再需用任何降眼压药。只有１眼复发性青光眼，需要用降眼压药控制。提出丝裂霉素确实能抑制青光眼滤过术后疤痕形成，大大提高了青光眼滤过手术的成功率，值得推广使用。讨论了国外报道所致的低眼压等并发症，介绍了我们的使用方法及其预防并发症发生。
Glaucoma filtration scar formation is the leading cause of postoperative glaucoma failure, but also experts at home and abroad has been the subject of research. In this paper, 45 cases of glaucoma suitable for line filtration surgery, 54 eyes, tracheotomy using Japan imported mitomycin (MitomycinC) 0.05% concentration for 1 minute. Recurrent glaucoma, secondary glaucoma use 1 minute × 2 times or 2 minutes × 1 times. After 3 months follow-up after 2 years, 98% of cases accompanied by white filter, IOP was controlled, no longer need to use any antihypertensive drugs. Only 1 eye with recurrent glaucoma, need to use ocular hypotensive drug control. Proposed mitomycin indeed can inhibit the formation of scar after glaucoma filtration surgery, greatly improving the success rate of glaucoma filtration surgery, it is worth promoting the use of. Discussed the foreign reports of intraocular pressure and other complications, introduced our use and prevention of complications.