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目的:探讨早期经口进食在MAP患者治疗中的安全性及有效性。方法:收集2015年4月至2018年6月间山西白求恩医院普通外科收治的100例MAP患者，根据经口进食时间分为早期经口进食组(患者腹痛、腹胀症状缓解，伴胃肠功能恢复，血清淀粉酶、脂肪酶未降至参考值上限2倍以下时开始经口进食)和传统经口进食组(患者腹痛、腹胀症状缓解，伴胃肠功能恢复，血清淀粉酶、脂肪酶降至参考值上限2倍以下时开始经口进食)，每组50例。比较两组患者进食后腹痛或腹胀再次发生率、血清淀粉酶及CRP水平升高率、器官功能障碍发生率、病死率和平均住院时间的差异。结果:早期经口进食组和传统经口进食组患者的性别、年龄、病因以及进食后腹痛及腹胀、血清淀粉酶升高、血CRP升高、器官功能障碍发生率的差异均无统计学意义，且两组均无死亡病例，但早期经口进食组患者的进食时间、住院天数均显著短于传统经口进食组[(3.00±0.18)d比(4.84±0.27)d，(8.24±0.33)d比(9.00±0.26)d]，差异均有统计学意义(n P值均<0.05)。n 结论:MAP患者早期经口进食不仅不会加重病情，反而有助于纠正患者营养状况，具有较高的安全性和有效性。“,”Objective:To investigate the safety and efficacy of early oral feeding in the treatment of mild acute pancreatitis (MAP).Methods:Data of 100 MAP patients from April 2015 to June 2018 admitted in Department of General Surgery in Shanxi Bethune Hospital were collected. According to the time of food intake through the mouth, the patients were divided into early oral feeding group (food intake started when the symptoms of abdominal pain and abdominal distension were alleviated with gastrointestinal functional recovery, but serum amylase and lipase did not decrease to a level below 2 times of normal upper limits) and traditional oral feeding group (food intake started when the symptoms of abdominal pain and abdominal distension were alleviated with gastrointestinal functional recovery, but serum amylase and lipase decreased to a level below 2 times of normal upper limits), with 50 cases in each group. The incidence of abdominal pain or bloating, serum amylase, CRP, organ dysfunction, morbidity and mortality, and median length of hospital stay after eating were compared between the two groups.Results:There were no statistically significant differences on gender, age, etiology, abdominal pain and distension, increased serum amylase, increased blood CRP, and number of organ dysfunction cases between two groups, and there were no deaths in either group. However, the feeding time and length of hospital stay in the early oral feeding group were significantly shorter than those in the traditional oral feeding group, and the differences were statistically significant [(3.00±0.18)d versus (4.84±0.27)d, (8.24±0.33) D versus (9.00±0.26)d, both n P<0.05].n Conclusions:Early oral feeding in MAP patients did not aggravate the disease, but helps to correct the nutritional status of the patients, with higher safety and effectiveness.