成都市龙泉驿区1998~2007年乙型肝炎流行趋势分析

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[目的]掌握成都市龙泉驿区乙型肝炎的流行趋势,为制订有效防治措施提供科学依据。[方法]采用描述性流行病学研究方法对1998~2007年报告的乙肝疫情资料进行动态分析。[结果]10年累计报告乙肝病例2800例,年均发病率56.13/10万,发病率呈上升趋势,1999年发病率最低,为26.67/10万,2004年最高,为90.38/10万,各年份之间的发病率差异有统计学意义(P﹤0.005);除2005年外,近5年的定基比均大于2,环比大于1;男性发病率为37.33/10万,女性发病率为18.80/10万,差异有统计学意义(P﹤0.005),男女性别比为1.99︰1;发病年龄以15~45岁最多,占72.32%,其次是45岁以上,占23.58%;职业构成以农民为主,占40.61%,其次是工人和学生,分别占16.11%、9.14%,不同职业的构成差异有统计学意义(P﹤0.005);中心城区与边远山区病例分布差异有统计学意义(P﹤0.005);无明显的季节性。[结论]乙肝的发病率呈上升趋势,发展、增长速度快;乙肝流行形势十分严峻。在做好乙肝疫苗扩大免疫规划的同时,应重点加强对农村男性中青年免疫预防接种;提高易感人群、高危人群免疫力的综合性防制措施。 [Objective] To master the epidemic trend of Hepatitis B in Longquanyi District of Chengdu and provide a scientific basis for formulating effective prevention and cure measures. [Methods] Descriptive epidemiological methods were used to analyze the data of hepatitis B outbreak reported from 1998 to 2007. [Results] 2800 cases of hepatitis B cases were reported in 10 years, with an average annual incidence rate of 56.13 / 100000. The incidence rate showed an upward trend, with the lowest incidence rate in 1999 being 26.67 / 100000 and the highest in 2004 at 90.38 / 100000 (P <0.005). In addition to 2005, the fixed base ratio was more than 2 in the past five years, and the ring ratio was greater than 1. The incidence of males was 37.33 / lakh and the incidence of females was 18.80 / 100000, the difference was statistically significant (P <0.005), male to female ratio was 1.99︰1; the age of onset was 15-45 years old, accounting for 72.32%, followed by 45 years old, accounting for 23.58%; occupational composition of peasants , Accounting for 40.61%, followed by workers and students, accounting for 16.11% and 9.14% respectively. There were significant differences in the composition of different occupations (P <0.005). There were significant differences in the distribution of cases between central urban areas and remote mountainous areas <0.005); no obvious seasonal. [Conclusion] The incidence of hepatitis B is on the rise, with rapid development and rapid growth. The prevalence of hepatitis B is very serious. While doing a good job of hepatitis B vaccine to expand the immunization program, we should focus on strengthening immunization vaccinations among young men and women in rural areas and comprehensive prevention and control measures to improve the immunity of susceptible and high-risk groups.
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