论文部分内容阅读
目的探讨0.9%氯化钠溶液(NS)和5%葡萄糖溶液(GS)配制吡柔比星(THP)在经尿道膀胱肿瘤电切术(TUR-Bt)后膀胱灌注的不良反应。方法选取2011年6月—2013年6月双流县第一人民医院收治的浅表性膀胱尿路上皮癌患者60例,随机分为NS组和GS组,各30例。NS组给予THP 40mg+NS 40ml;GS组给予THP 40mg+GS 40ml。观察两组不良反应并随访。结果 GS组不良反应发生率低于NS组,差异有统计学意义(P<0.05)。结论 GS配制THP在TUR-Bt后膀胱灌注对于预防浅表性膀胱尿路上皮癌术后复发有良好的临床疗效,且不良反应更少。
Objective To investigate the adverse reactions of bladder perfusion after transurethral resection of bladder tumor (TUR-Bt) with 0.9% sodium chloride solution (NS) and 5% glucose solution (GS) Methods Sixty patients with superficial bladder urothelial carcinoma who were admitted to the First People’s Hospital of Shuangliu County from June 2011 to June 2013 were randomly divided into NS group and GS group, with 30 cases in each group. NS group received THP 40mg + NS 40ml; GS group given THP 40mg + GS 40ml. Adverse reactions were observed and followed up. Results The incidence of adverse reactions in GS group was lower than that in NS group, the difference was statistically significant (P <0.05). Conclusions The preparation of THP after TUR-Bt administration by GTP has good clinical curative effect in preventing postoperative recurrence of superficial bladder urothelial carcinoma with fewer adverse reactions.