论文部分内容阅读
目的:探讨热淋清颗粒对肾结石术后尿路感染的预防作用及对术后排石、疼痛的影响。方法:选择2012年5月—2015年4月接受手术治疗的72例肾结石患者,按照随机数字表法分为对照组与观察组各36例,对照组术后静滴盐酸左氧氟沙星氯化钠注射液干预,观察组在此基础上加用热淋清颗粒治疗,两组均治疗1周,观察两组治疗效果,统计结石排出率及排净时间,观察患者尿痛、尿频、血尿、肾区疼痛、叩击痛等症状及体征评分改善情况,监测治疗期间不良反应发生情况,记录两组术后1个月内尿路感染发生率。结果:1观察组总有效率略高于对照组,但对比差异无统计学意义(P>0.05);2观察组治疗1周血尿、尿频、尿痛、尿急、肾区疼痛、叩击痛等症状积分均低于对照组,对比差异有统计学意义(P<0.05);3观察组结石排出率高于对照组(P<0.05),结石排净时间短于对照组,对比差异有统计学意义(P<0.05);4两组治疗期间不良反应发生率相近(P>0.05),均未见严重不良反应;5观察组尿路感染发生率低于对照组,对比差异有统计学意义(P<0.05)。结论:热淋清颗粒用于防治PCNL术后尿路感染整体效果好,可促进结石排出,减轻尿痛、肾区疼痛等症状,且安全性高,不良反应少。
Objective: To investigate the preventive effect of Reizhen Granules on postoperative urinary tract infection after nephrolithiasis and its influence on postoperative row stone and pain. Methods: Seventy-two patients with nephrolithiasis who were surgically treated from May 2012 to April 2015 were divided into control group and observation group according to the random number table method, and 36 patients in the control group received intravenous infusion of levofloxacin hydrochloride Liquid intervention, the observation group on this basis with heat rashqing granule treatment, both groups were treated for 1 week, the two groups were observed the therapeutic effect, statistics stone discharge rate and drainage time, observe the patients with dysuria, urinary frequency, hematuria, Pain, percussion pain and other symptoms and signs score to improve the situation, monitoring the incidence of adverse reactions during treatment, recording the incidence of urinary tract infection within 1 month after surgery in both groups. The total effective rate of the observation group was slightly higher than that of the control group, but there was no significant difference between the two groups (P> 0.05); 2 The observation group had hematuria, frequent urination, urinary urgency, renal area pain, (P <0.05). 3 The stone discharge rate in the observation group was higher than that in the control group (P <0.05), and the time for discharging stones was shorter than that in the control group, with statistical differences (P <0.05) .4 The incidence of adverse reactions in the two groups during treatment was similar (P> 0.05), and no serious adverse reactions were observed. The incidence of urinary tract infection in the observation group was lower than that in the control group, the difference was statistically significant (P <0.05). Conclusion: The heat clearing granule for PCNL postoperative urinary tract infection overall effect is good, can promote the discharge of stones, reduce the pain of the urination and kidney, and other symptoms, and high safety, fewer adverse reactions.