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目的:探讨养血通利胶囊治疗多囊卵巢综合征患者的效果。方法:将107例多囊卵巢综合征患者随机分为治疗组76例和对照组31例,治疗组服用养血通利胶囊治疗,对照组服用克罗米芬治疗。计算用药前后体重指数(BMI)及F-G评分,并检测口服葡萄糖耐量试验(OGTT)及血清性激素水平。结果:治疗组治愈率64.5%、总有效率92.1%、妊娠率67.8%,明显高于对照组的51.6%、77.4%、30.0%(P<0.01,P<0.05)。结论:养血通利胶囊治疗多囊卵巢综合征疗效明显优于克罗米芬,并能明显降低BMI及明显改善多毛现象,还能使OGTT恢复正常,降低血清促黄体生成素(LH)、睾酮(T)水平,且安全无毒副作用,使用方便。
Objective: To investigate the effect of Yangxuetongli capsule on patients with polycystic ovary syndrome. Methods: A total of 107 patients with PCOS were randomly divided into treatment group (n = 76) and control group (n = 31). The treatment group was treated with Yangxuetongli capsule while the control group was treated with clomiphene citrate. Body mass index (BMI) and F-G score were calculated before and after treatment, and oral glucose tolerance test (OGTT) and serum sex hormone levels were measured. Results: The cure rate of the treatment group was 64.5%, the total effective rate was 92.1%, the pregnancy rate was 67.8%, which was significantly higher than that of the control group (51.6%, 77.4%, 30.0%, P <0.01, P <0.05). Conclusion: Yangxuetongli capsule is superior to clomiphene for the treatment of polycystic ovary syndrome, and can significantly reduce the BMI and significantly improve the hirsutism, but also make OGTT return to normal, reduce serum luteinizing hormone (LH), testosterone T) level, and safe non-toxic side effects, easy to use.