葡萄糖耐量异常(IGT)是糖尿病的前期状态,主要表现为胰岛素的敏感性降低导致餐后血糖升高,它不但是发展为糖尿病的高风险因素,而且本身也是血管病变危险因子。近年来研究表明高表达的内皮黏附分子可能在加速糖尿病血管病变方面起潜在的作用[1],但在IGT阶段有无内皮黏附分子的异 Impaired glucose tolerance (IGT) is a pre-diabetic state mainly characterized by decreased insulin sensitivity leading to postprandial hyperglycemia, which is not only a high risk factor for the development of diabetes but also a risk factor for vascular disease. In recent years, studies have shown that high expression of endothelial adhesion molecules may play a role in accelerating diabetic vascular lesions [1], but in the IGT stage with or without endothelial adhesion molecule