在碱的存在下,以氯乙酸钠为醚化试剂,微波法制备了羧甲基菊粉。考察了醚化时间、碱化时间、溶剂体积分数、溶剂用量、碱用量以及溶剂种类对取代度的影响。当菊粉用量为2.7g,氯乙酸钠用量为1.7g,反应条件为微波炉功率90W碱化2.5min,醚化30min,碱用量0.4g,反应溶剂为2mL体积分数为90%的异丙醇时,产品取代度达0.51。 Carboxymethyl inulin was prepared by microwave method in the presence of alkali with sodium chloroacetate as etherification reagent. The effects of etherification time, alkalization time, solvent volume fraction, solvent amount, base amount and solvent type on the degree of substitution were investigated. When the inulin dosage was 2.7g, the dosage of sodium chloroacetate was 1.7g, the reaction conditions were microwave power 90W alkalization 2.5min, etherification 30min, base dosage 0.4g, reaction solvent 2mL volume fraction of isopropanol 90% , Product substitution degree of 0.51.