论文部分内容阅读
目的 :探讨MR弥散加权成像对儿童脑部脱髓鞘及变性疾病的应用价值 .方法 :采用Philips1.5T磁共振系统对 14例经临床检查和治疗确诊的脑部脱髓鞘和变性病变进行常规和弥散加权成像 (DWI) .结果 :炎性脱髓鞘病变主要位于白质内 ,T2WI表现为高信号 ,DWI显示为略高、等或略低信号 ;肝豆状核变性DWI表现为基底节区对称性略高信号和略低信号并存的特征性改变 ;肾上腺脑白质营养不良DWI表现为T2信号相反的信号改变 (即从后向前由等信号向略高信号变化 ) ;吸毒性脑病 (急性期 )DWI表现为齿状核、基底节区等对称性高信号 (细胞毒水肿信号 ) ;CO中毒病变DWI早期表现为半卵圆中心和侧脑室旁对称性高信号 ,慢性期表现为基底节区对称性点状低信号 ;缺血缺氧后脑室周围软化DWI示双侧脑室旁低信号改变 .结论 :DWI对儿童脑部脱髓鞘和变性病变具有较大的诊断和鉴别诊断价值 .
Objective: To investigate the value of MR diffusion-weighted imaging in the demyelinating and degenerative diseases of the brain in children.Methods: According to the Philips1.5T magnetic resonance system, 14 cases of demyelinating and degenerative brain degeneration were diagnosed by clinical examination and treatment. And DWI were observed.Results: Inflammatory demyelinating lesions mainly located in the white matter, T2WI showed high signal, DWI showed slightly higher, equal or slightly lower signal; Wilson’s disease DWI manifested as basal ganglia Symmetry slightly higher signal and slightly lower signal characteristic coexistence; Adrenal leukodystrophy DWI showed the opposite of the T2 signal change (ie, from the signal to the slightly higher signal from the backward); drug induced encephalopathy (acute DWI showed high symmetry signal (cytotoxic edema signal) such as dentate nucleus and basal ganglia; DWI of CO poisoning lesions showed high signal of semi-oval center and lateral ventromedial symmetry in early stage, Regional symmetry point-like low signal; hypoxic-ischemic duodenal periaqueductal DWI showed a low signal around the double-sided changes.Conclusion: DWI in children with demyelinating and degenerative brain lesions have a greater diagnostic and differential diagnosis .