目的：探讨早期圆锥角膜的Orbscan II角膜地形图特点及敏感指标。方法应用Orbscan II研究23例（43只眼）早期圆锥角膜患者和25例（50只眼）近视患者角膜地形图的参数改变特点，并进行统计分析。结果患者年龄、近视度数、散光度数均无统计学差异（P ＞0．05）。角膜地形图参数中：角膜最薄点厚度、角膜前表面高度、角膜后表面高度、3．0 mm区不规则性（3．0 mm Zone Irreg）、5．0 mm区不规则性（5．0 mm Zone Irreg）在两组之间均有统计学差异（ P＜0．05）。结论角膜最薄点厚度、角膜前表面高度、角膜后表面高度、3．0 mm区不规则性有助于区分早期圆锥角膜和近视患者，是诊断早期圆锥角膜的敏感地形图指标。“,”Objective To investigate the cornea topographic characteristics and sensitive indexes of Orbscan II of early keratoconus.Methods By using Orbscan II,a prospective study was performed in 23 cases (43eyes) early kerato-conus and 25 cases (50 eyes) myopia.The results were evaluated and analysed.Results There is no statistically sig-nificance between the two groups of early keratoconus and myopia in age, degree of myopia and astigmatism ( P>0.05).The study discover that there are statistically significance in the thinnest thickness of cornea、diff values of cor-nea anterior surface、diff values of cornea posterior surface、3.0mm Zone Irreg and 5.0mm Zone Irreg between early kera-toconus and myopia ( P<0.05).Co ncluis ons All thinnest corneal thickness,diff values of cornea anterior surface、diff values of cornea posterior surface、3.0mm Zone Irreg appear to be sensitive indexes for diagnosing early keratoconus.