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目的探究多烯磷脂酰胆碱药物用于对急性野生菌中毒患者治疗的应用效果。方法通过随机数字表方法将于2015-2017年期间收治确诊急性野生菌中毒患者60例分为对照组与观察组,每组30例,分别应用常规对症治疗和联用多烯磷脂酰胆碱治疗手段。疗程后观察两种干预方案对患者病情的作用。结果分别于两组患者治疗前后对其各项临床指标包括:血清ALT、AST、ALP以及BDTL进行检测,提示患者指标在完成干预后均有所改善且观察组更具优越性,统计学软件处理提示组间差异有意义(P<0.05);分别记录患者症状消失平均时间谷草转氨酶与谷丙转氨酶恢复时间,观察组数据提示更具优越性,统计学软件对组间差异处理后有意义(P<0.05)。结论多烯磷脂酰胆碱对于提升多急性野生菌中毒患者疗效有重要价值,在更短时间内改善患者相关体征恢复正常,缩短症状改善所需时间,保障患者健康和机体舒适度,值得推广。
Objective To investigate the therapeutic effect of polyene phosphatidylcholine on patients with acute wild-type poisoning. Methods Sixty patients diagnosed with acute wild-type fungal poisoning during 2015-2017 were divided into control group and observation group by random number table method, with 30 cases in each group. The patients were treated with conventional symptomatic treatment and polyene phosphatidylcholine means. After treatment, the effects of two interventions on the patient’s condition were observed. The results of the two groups of patients before and after treatment of its clinical indicators include: serum ALT, AST, ALP and BDTL were detected, suggesting that the patient index improved after completion of the intervention and the observation group more advantages, statistical software processing (P <0.05). The recovery time of aspartate aminotransferase (AST) and alanine aminotransferase (AST) in the mean time of symptom disappearance were recorded respectively. The data of the observation group showed more superiority. The statistical software showed significant difference (P <0.05). CONCLUSION: Polyene phosphatidylcholine is of great value in improving the curative effect of patients with acute acute mycosis poisoning. It is worth to be improved in a short period of time to improve patients’ signs and symptoms, shorten the time needed for symptom improvement, and protect the health and body comfort of patients.