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目的观察盐酸氨溴索注射液辅助治疗小儿支气管肺炎的临床效果。方法选取医院收治并确诊为小儿支气管肺炎患儿408例,随机分为对照组和观察组,每组204例。2组均给予解痉、吸氧、退热、抗感染、营养支持等常规治疗,对照组在常规治疗基础上加用溴己新进行祛痰治疗,观察组在常规治疗基础上加用盐酸氨溴索注射液辅助治疗,比较2组症状改善时间及用药效果,同时比较2组住院时间及用药不良反应发生情况。结果观察组总有效率为98.04%,高于对照组的80.39%(P<0.01);观察组咳嗽消失时间、退热时间、肺部啰音消失时间及住院时间均短于对照组(P<0.05);2组均无明显不良反应发生。结论对小儿支气管肺炎在常规治疗基础上联合盐酸氨溴索注射液辅助治疗的效果显著,能明显改善患儿咳嗽、发热、气促等症状,缩短患儿住院时间,且用药安全。
Objective To observe the clinical effect of ambroxol hydrochloride injection in the treatment of bronchial pneumonia in children. Methods A total of 408 children with bronchial pneumonia admitted to our hospital were selected and randomly divided into control group and observation group, with 204 cases in each group. Both groups were given conventional therapy of antispasmodic, oxygen inhalation, antipyretic, anti-infective and nutritional support. The control group was treated with expectorant on the basis of conventional treatment with bromhexine. The observation group was treated with ammonia hydrochloride Bromosanol injection adjuvant therapy, to compare the two groups to improve the symptoms and medication time, at the same time, the two groups of hospital stay and adverse reactions to medication. Results The total effective rate in the observation group was 98.04%, which was higher than that in the control group (80.39%, P <0.01). The disappearance time of cough, the antipyretic time, the disappearance of pulmonary rales and hospital stay in the observation group were shorter than those in the control group (P < 0.05). No adverse reactions occurred in both groups. Conclusion The adjuvant therapy with ambroxol hydrochloride injection on bronchopneumonia in children with bronchial asthma is effective on the basis of conventional treatment. It can significantly improve children ’s cough, fever, shortness of breath and other symptoms, and shorten the hospitalization time and medication safety.