癌前病变具有比正常组织恶变危险性高的特点。已证明口腔红斑、白斑和扁平苔藓具有恶变的潜在可能性。外科切除是否具有减少癌变的能力仍无定论。关于评价外科切除癌前病变的详细资料也很少。该研究的目的是要证明早期适当的外科治疗是否有预防恶变的可能性及对外科治疗口腔癌前病变的利弊作一正确的评价。材料和方法患者共61人。包括活检中出现轻度上皮异常增生到原位癌,及位于舌下或舌上未出现上皮异常增生的损害,临床诊断红斑10例,红白斑15例,结节性白斑9例,疣状白斑9例,均质性白斑13例,扁平苔藓5例。平均年龄65.3岁(34～94)。女32人,男29人。损害位于颊或唇的23例,颊和唇转折处9例,牙槽嵴11例,舌下26例,舌8例,腭部6例。72％为吸烟 Precancerous lesions have a higher risk of malignancy than normal tissue. Oral erythema, leukoplakia, and lichen planus have been shown to have the potential for malignant transformation. Whether surgical excision has the ability to reduce cancer is still inconclusive. There are few details about evaluating surgical resection of precancerous lesions. The purpose of this study was to demonstrate whether early appropriate surgical treatment has the potential to prevent malignant transformation and to make a correct assessment of the advantages and disadvantages of surgical treatment of precancerous oral lesions. Materials and Methods A total of 61 patients were included. Including mild epithelial dysplasia to carcinoma in situ, and no epithelial dysplasia in the sublingual or tongue. Clinically diagnosed erythema in 10 cases, red and white spot in 15 cases, nodular leukoplakia in 9 cases, and verrucous leukoplakia In 9 cases, there were 13 cases of homogeneous leukoplakia and 5 cases of lichen planus. The average age is 65.3 years (34 to 94). There are 32 females and 29 males. Damage occurred in 23 cases located in the cheeks or lips, 9 cases in the cheek and lip transitions, 11 cases in the alveolar ridge, 26 cases in the sublingual, 8 cases in the tongue, and 6 cases in the ankle. 72% for smoking