近10年来,愈来愈多的证据表明免疫系统与中枢神经系统间的双向作用。白细胞介素-2(IL-2)不但在免疫系统调节中起重要作用,而且近年来的研究证实在上述双向关系中起极为重要的作用。 刘新垣等曾报道IL-2能竞争抑制阿片肽类物质对鼠脑阿片肽受体的特异性结合,由此我们推测IL-2可能具有中枢镇痛作用。本实验以雄性160～180gSD大鼠为模型,采用侧脑室给药,以钾 In the past decade, more and more evidence shows that the immune system interacts with the central nervous system. Interleukin-2 (IL-2) not only plays an important role in the regulation of the immune system, but recent studies have demonstrated that it plays an extremely important role in the above two-way relationship. Liu et al. Reported that IL-2 competitively inhibits the specific binding of opioid peptides to opioid receptors in rat brain. Therefore, we speculate that IL-2 may have central analgesic effect. In this study, male 160 ~ 180gSD rats as a model, the use of lateral ventricular administration, potassium