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目的了解入伍新兵人群结核杆菌(MTB)IgG抗体的流行分布情况,为今后预防MTB感染提供科学依据。方法采用血清流行病学调查方法,利用酶联免疫吸附试验(ELISA)技术,对我区近8年来自16个省市的364名入伍新兵血清进行了MTB-IgG抗体检测并进行统计分析。结果来自16个省市8年间入伍的364名新兵,发现历年间抗体阳性率存在显著性差异;天津市(86.96%)、湖南省(86.36%)、江苏省(78.26%)和内蒙古自治区(78.26%)阳性率较高,其中甘肃省(21.74%)、黑龙江省(26.09%)和四川省(34.78%)相对较低,显著性检验差别有统计学意义,阳性率21.74%~86.96%,平均阳性率为57.14%。此外,沿海地区与内陆地区间抗体阳性率也存在显著差异。入伍前工作与否,抗体阳性检出率无显著性差别。结论新兵人群抗体阴性率较高,易感性高,部队各级卫生管理部门应高度关注结核病的预防工作。
Objective To understand the epidemiological distribution of Mycobacterium tuberculosis (MTB) IgG in recruits and to provide a scientific basis for future prevention of MTB infection. Methods The serological epidemiological survey method was used to detect the MTB-IgG of 364 recruit serogroups from 16 provinces and cities in our district in recent 8 years by enzyme-linked immunosorbent assay (ELISA), and statistical analysis was made. The results were obtained from 364 recruits enlisted in 16 provinces and cities in 8 years. There was a significant difference in the positive rate of antibody between the two years in Tianjin (86.96%), Hunan (86.36%), Jiangsu (78.26%) and Inner Mongolia Autonomous Region %) Were higher in Gansu Province (21.74%), Heilongjiang Province (26.09%) and Sichuan Province (34.78%). The significant difference was statistically significant (21.74% -86.96% The positive rate was 57.14%. In addition, there are also significant differences in antibody positive rates between coastal and inland areas. Pre-enlistment work or not, antibody positive detection rate no significant difference. Conclusions The new recruits have high antibody negative rate and high susceptibility. The health management departments at all levels of the armed forces should pay close attention to the prevention of tuberculosis.