作者观察了3例以耳部症状为早期表现的Wegner’s肉芽肿。第一例,早期为双侧中耳炎,混合性聋,考的松治疗能缓解症状。两年后才出现全身及鼻部症状,并以皮肤瘀斑样损害中组织学证实为典型的Wegnes’s肉芽肿。第二例,首先发生右侧分泌性中耳炎,作了鼓膜切开及置通气管,继之发生左耳鸣、耳聋、鼓膜内陷,电测听示双耳感觉神经性聋。发病半年后病变累及全身及其它器官。第三例,以双耳痛、听力下降起病,双侧外耳道有肉芽组 The authors observed 3 cases of Wegner’s granuloma with ear symptoms as an early manifestation. The first case, early for bilateral otitis media, mixed deaf, test the pine treatment can relieve symptoms. Two years later, systemic and nasal symptoms were present and wegnes’ granulomas were confirmed by histology in ecchymoses. The second case, the first occurrence of secretory otitis media right, made tympanotomy and set the ventilation tube, followed by the left tinnitus, deafness, tympanic membrane retraction, electrical audiometry showed binaural sensory nerve deafness. Six months after the onset of disease involving the whole body and other organs. The third case, to double ear pain, hearing loss onset, bilateral external auditory meatus granulation group