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目的比较门诊短期持续皮下胰岛素注射(CSII)治疗及门诊多次皮下注射胰岛素(MDI)治疗T2DM的疗效。方法收集门诊CSII(A组)、住院CSII(B组)及门诊MDI(C组)患者,比较血糖控制情况、达标时间、胰岛素用量、低血糖发生率、治疗费用。结果 A组与B组比较,血糖达标时间、胰岛素用量、低血糖发生率等差异无统计学意义(P>0.05),治疗费用A组小于B组(P<0.01);A组与C组比较,血糖控制情况、达标时间、低血糖发生率等差异有统计学意义(P<0.01)。结论门诊胰岛素泵短期强化治疗能平稳有效控制血糖,且费用较低,降糖效果优于门诊MDI。
Objective To compare the efficacy of short-term continuous subcutaneous insulin injection (CSII) and outpatient subcutaneous injection of insulin (MDI) in the treatment of T2DM. Methods Patients in outpatient CSII (group A), inpatient CSII (group B) and outpatient MDI (group C) were enrolled in this study. Blood glucose control, compliance time, insulin dosage, incidence of hypoglycemia, and treatment costs were compared. Results Compared with group B, there was no significant difference in the standard of glycemic control, insulin dosage, incidence of hypoglycemia between group A and group B (P> 0.05), and the cost of treatment group A was less than that of group B (P <0.01) , Blood glucose control, compliance time, the incidence of hypoglycemia and other differences were statistically significant (P <0.01). Conclusions Short-term intensive insulin treatment of outpatients can control blood glucose smoothly and effectively with low cost and better hypoglycemic effect than outpatient MDI.