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目的:对照评估三种胰岛素强化方案治疗2型糖尿病的临床应用价值。方法:2013年4月至2014年5月于该院就诊的2型糖尿病患者中选取78例,随机分为三组各26例,Ⅰ组实施胰岛素泵治疗,Ⅱ组实施多次皮下注射胰岛素,Ⅲ组实施甘精胰岛素联合格列美脲,对比其治疗效果。结果:将三组患者治疗前后的FBG、PBG、HbA1C进行对比,差异具有统计学意义(P<0.05),Ⅰ组患者的血糖达标时间短于Ⅱ组及Ⅲ组(P<0.05)。结论:三种胰岛素强化方案治疗2型糖尿病均具有显著的临床效果,胰岛素泵治疗的时间最短,具体方案的选择可根据患者的病情而定。
OBJECTIVE: To evaluate the clinical value of three insulin regimens in the treatment of type 2 diabetes mellitus. Methods: From April 2013 to May 2014, 78 patients with type 2 diabetes who were treated in the hospital were randomly divided into three groups of 26 patients. Group I received insulin pump treatment. Group II received multiple subcutaneous injections of insulin, Group Ⅲ insulin glargine combined with glimepiride, compared to its therapeutic effect. Results: The FBG, PBG and HbA1C levels in three groups before and after treatment were significantly different (P <0.05). The duration of glycemic control in group Ⅰ was shorter than that in groups Ⅱ and Ⅲ (P <0.05). CONCLUSION: Three kinds of insulin intensified regimens have significant clinical effects in the treatment of type 2 diabetes. Insulin pump therapy has the shortest duration. The choice of specific regimen may be based on the patient’s condition.