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目的 探讨米索前列醇用于足月妊娠催产的安全性及效果。方法 回顾性分析 10 0例使用米索前列醇催产和 10 0例使用催产素催产的足月妊娠产妇的临床资料。结果 米索前列醇组晚期妊娠催产的有效率为 95% ,显著高于对照组的 79% (P <0 .0 5) ,米索组催产时间、总产程显著短于对照组 (P <0 .0 5)。两组剖宫产率、产后出血、新生儿情况比较无显著性差异。但急产发生率 ,米索组 ( 2 1% )显著高于对照组( 1% ) (P <0 .0 1)。结论 米索前列醇舌下含服给药用于足月妊娠催产能促进宫颈成熟及发动子宫收缩 ,其效果优于催产素
Objective To investigate the safety and efficacy of misoprostol in term pregnancy induced labor. Methods A retrospective analysis of 100 cases of misoprostol oxytocin and 10 cases of oxytocin oxytocin oxytocin clinical data. Results The rate of oxytocin in late misoprostol group was 95%, significantly higher than 79% in control group (P <0.05), while the misoprostol time and total labor in misoprostol group were significantly shorter than those in control group (P <0. 05) .0 5). Cesarean section rate, postpartum hemorrhage, neonatal no significant difference between the two groups. However, the incidence of acute birth was significantly higher in the misoprostol group (21%) than in the control group (1%) (P <0.01). Conclusion Misoprostol administered sublingually for gestational cesarean section can promote cervical ripening and uterine contractions, which is superior to oxytocin