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目的观察尿微量白蛋白检测与早期肾损害的关系。方法本组264例,依据糖化血红蛋白(HbA1c)分组,检测各组尿微量白蛋白(U-mAlb),并进行分析。结果 A组52例,U-mAlb≤20mg/L49例,>20 mg/L3例;B组114例,U-mAlb>20 mg/L102例;C组U-mAlb>20 mg/L96例。并且随着HbA1c增高而增加。经统计学处理,A组与B、C二组差异有统计学意义(P<0.01),而B、C两组则无统计学意义(P>0.05)。结论 U-mAlb可以早期发现糖尿病肾损害,HbA1c控制在7.5%以下有利于延缓糖尿病肾病进展。
Objective To investigate the relationship between urinary microalbuminuria and early renal damage. Methods 264 cases of this group, according to glycosylated hemoglobin (HbA1c) group, urine microalbumin (U-mAlb) were detected and analyzed. Results A group of 52 cases, U-mAlb ≤ 20mg / L 49 cases,> 20 mg / L3 cases; B group 114 cases, U-mAlb> 20 mg / L102 cases; C group U-mAlb> 20 mg / L96 cases. And increased as HbA1c increased. After statistical analysis, there was significant difference between group A and group B and C (P <0.01), but not between group B and C (P> 0.05). Conclusion U-mAlb can detect diabetic nephropathy early, HbA1c control below 7.5% is conducive to delay the progress of diabetic nephropathy.