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目的回顾性分析住院患者高尿酸血症的患病率、诊断率及疾病相关并发症的概况。方法 110例住院患者,对其尿酸水平进行检测,根据检测结果将患者分为高尿酸血症组与血尿酸正常组,对高尿酸血症的患病率、相关并发症发生情况及诊断率进行分析。结果将110例患者按血尿酸水平分为高尿酸血症组(25例)与血尿酸正常组(85例)。与血尿酸正常组比较,高尿酸血症组患者的血清尿酸、年龄、空腹血清葡萄糖及血清胆固醇水平均更高,差异均具有统计学意义(P<0.05);两组血清甘油三酯、高密度脂蛋白及极低密度脂蛋白、尿素氮/肌酐水平比较差异均无统计学意义(P>0.05)。与血尿酸正常组比较,高尿酸血症组患者高血压、高脂血症、肾功能不全、肾结石的罹患率均升高,差异均具有统计学意义(P<0.05);两组患者糖尿病、脑血管意外、冠心病的罹患率比较差异无统计学意义(P>0.05)。住院患者高尿酸血症临床诊断率为16.66%(450/2701),在450例诊断为高尿酸血症的患者中,给予药物治疗181例(40.22%),饮食干预130例(28.89%)。结论高尿酸血症患者高血压及肾功能不全罹患率高,临床医生对高尿酸血症的诊断率和干预治疗率较低。
Objective To retrospectively analyze the prevalence, diagnosis rate and disease-related complications of hyperuricemia in hospitalized patients. Methods A total of 110 hospitalized patients were enrolled and their uric acid levels were measured. According to the test results, the patients were divided into hyperuricemia group and normal uric acid group. The prevalence of hyperuricemia, the incidence of related complications and the diagnosis rate analysis. Results According to the level of serum uric acid, 110 patients were divided into hyperuricemia group (n = 25) and serum uric acid normal group (n = 85). The levels of serum uric acid, age, fasting serum glucose and serum cholesterol in patients with hyperuricemia were significantly higher than those in patients with normal blood uric acid (P <0.05). Serum triglycerides, high There was no significant difference in the levels of LDL, VLDL and urea nitrogen / creatinine (P> 0.05). Compared with normal blood uric acid group, the incidence of hypertension, hyperlipidemia, renal insufficiency and kidney stones in hyperuricemia group were all significantly higher than those in normal control group (P <0.05). The incidence of diabetes mellitus , Cerebrovascular accident, coronary heart disease attack rate difference was not statistically significant (P> 0.05). Inpatients with hyperuricemia clinical diagnosis rate was 16.66% (450/2701), in 450 cases of patients diagnosed as hyperuricemia, drug treatment of 181 cases (40.22%), diet intervention in 130 cases (28.89%). Conclusion The incidence of hypertension and renal insufficiency in patients with hyperuricemia is high, and the rate of diagnosis and intervention of hyperuricemia by clinicians is low.