神经肽Ｙ(ＮＰＹ)是神经系统中含量最多的肽类之一 ,脑源性神经生长因子 (ＢＤＮＦ)在中枢神经系统中含量也不少。新近许多研究表明 ,两者与癫痫密切相关。为此 ,我们就近几年来ＮＰＹ和ＢＤＮＦ ,特别是前者与癫痫关系的研究进展作一综述。1　ＮＰＹ与癫痫ＮＰＹ是由Ｔａｔｅ Neuropeptide Y (NPY) is one of the most abundant peptides in the nervous system. Brain derived nerve growth factor (BDNF) is also found in the central nervous system. Recently, many studies have shown that both are closely related to epilepsy. For this reason, we review the recent progress of NPY and BDNF, especially the former with epilepsy. 1 NPY with epilepsy NPY is produced by Tate