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目的了解某战区驻地恙虫病的临床与流行病学特征,为指导部队做好防治工作提供科学依据。方法选择临床确诊恙虫病患者进行个案调查,并填写流行病学调查表。同时采集患者静脉血液,分离血清,做血清学检验,并结合课题组的文献和相关资料进行整理统计分析。结果某战区部分驻地恙虫病的临床与流行病学特征与我国南方的夏季型不尽相同,主要具有以下特点:①患者临床表现以发热和全身中毒症状为主,溃疡焦痂约占54.81%;②合并器官损害发生率为45.93%,其中有多个器官损害(multi-organs lesion,MOL)者占26.67%;③流行季节9~12月,占发病数85.19%(115/135)以上,属秋冬型;④病例以散发为主,偶见局部小暴发;⑤患者以青壮年农民居多,占84.44%;⑥流行血清型以Gilliam为主,并可能伴有其他型混合感染。结论基本模清某战区部分驻地秋冬型恙虫病临床与流行病学特征,提示当地军民应重视本病的防治工作。
Objective To understand the clinical and epidemiological characteristics of tsutsugamushi disease in a war zone and provide a scientific basis for guiding the army in prevention and treatment. Methods The patients with confirmed tsutsugamushi disease were selected for case investigation and the epidemiological questionnaire was filled in. At the same time, the patients’ venous blood was collected, the serum was separated, and the serological tests were done. The statistical analysis was done with the literature and relevant materials of the research group. Results The clinical and epidemiological characteristics of some tsutsugamushi resident stations in a certain theater were different from those in southern China. The main characteristics were as follows: ① The clinical manifestations were fever and systemic poisoning, with the esophageal mucosa accounting for 54.81%; ② The incidence of combined organ damage was 45.93%, with multiple organ lesion (MOL) accounted for 26.67%; ③ The epidemic season 9 to December, accounting for more than 85.19% (115/135) incidence, Autumn and winter type; ④ cases of excretion-based, occasional minor outbreaks; ⑤ patients are mostly young adults, accounting for 84.44%; ⑥ epidemic serotypes Gilliam-based, and may be accompanied by other types of mixed infections. Conclusions The basic modality of the autumn and winter resident tsutsugamushi disease and epidemiological characteristics of some resident stations in war zone suggests that the local military and civilian should pay attention to the prevention and treatment of this disease.