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目的观察更昔洛韦治疗老年带状疱疹的临床疗效。方法将96例老年带状疱疹患者随机分为两组,治疗组48例,给予更昔洛韦治疗;对照组48例,给予阿昔洛韦治疗。两组均用药10d后观察临床症状、体征变化,判定治疗效果。结果治疗组在止疱时间、止痛时间、结痂时间明显短于对照组,差异均有统计学意义(P均<0.01),治疗组与对照组治愈率分别为72.92%和56.25%、有效率分别为89.58%和72.91%,两组治愈率和有效率分别比较,差异也均有统计学意义(P均<0.05)。结论更昔洛韦治疗带状疱疹临床疗效明显优于阿昔洛韦。
Objective To observe the clinical efficacy of ganciclovir in the treatment of elderly herpes zoster. Methods 96 cases of elderly herpes zoster were randomly divided into two groups, the treatment group of 48 patients given ganciclovir treatment; the control group of 48 patients were given acyclovir treatment. Two groups were observed after 10d of clinical symptoms, signs changes, determine the treatment effect. Results The treatment group had shorter blistering time, analgesic time and scabbing time than the control group (all P <0.01), and the cure rates of the treatment group and the control group were 72.92% and 56.25% respectively. The effective rate Respectively, 89.58% and 72.91%, respectively. The cure rates and effective rates of the two groups were respectively compared, the differences were also statistically significant (all P <0.05). Conclusion The clinical efficacy of ganciclovir in the treatment of shingles is better than that of acyclovir.