脑实质内发生的神经胶质瘤由于浸润正常脑组织,选择性破坏常很困难,尚无根治方法。可视激光和光增敏物质并用的光化学疗法(PDT)的优点在于可在手术中进行,并可将可视激光特性与亲肿瘤细胞性药物的激发光及肿瘤细胞固有荧光综合起来应用,使浸润性肿瘤的诊断及选择性破坏成为可能。自血卟啉(HPD)作为光增敏物质应用以来,人们逐渐尝试将其应用于对神经胶质瘤的治疗。本文主要 The gliomas that occur within the brain parenchyma are often difficult to selectively destroy due to infiltration of normal brain tissue. There is no cure. The advantages of photochemotherapy (PDT) with visible laser and light sensitizers are that they can be performed during surgery, and the visible laser characteristics can be combined with the excitation light of the pro-tumor cellular drug and the intrinsic fluorescence of the tumor cells to apply infiltration. Diagnosis and selective destruction of sexual tumors become possible. Since the application of hematoporphyrin (HPD) as a photosensitizing substance, people gradually tried to apply it to the treatment of glioma. This article is mainly